Genipin improves reproductive health problems caused by circadian disruption in male mice
نویسندگان
چکیده
منابع مشابه
Are problems with male reproductive health caused by endocrine disruption?
More than 20 years ago, it was suggested that the normal reproductive development of the male embryo may be aVected by exposure to oestrogens, the focus initially being on the mother’s endogenous oestrogen. In 1993, Sharpe and Skakkebaek proposed the hypothesis that increased oestrogen exposure in early life increases the risk of the two genital malformations hypospadias and cryptorchidism, and...
متن کاملCrocin Improves Damage Induced by Nicotine on A Number of Reproductive Parameters in Male Mice
Objective Crocin, a carotenoid isolated from Crocus sativus L. (saffron), is a pharmacologically active component of saffron. Nicotine consumption can decrease fertility in males through induction of oxidative stress and DNA damage. The aim of this study is to determine the effects of crocin on reproductive parameter damages in male mice exposed to nicotine. MaterialsAndMethods In this experime...
متن کاملcrocin improves damage induced by nicotine on a number of reproductive parameters in male mice
objective: crocin, a carotenoid isolated from crocus sativus l. (saffron), is a pharmacologically active component of saffron. nicotine consumption can decrease fertility in males through induction of oxidative stress and dna damage. the aim of this study is to determine the effects of crocin on reproductive parameter damages in male mice exposed to nicotine. materials and methods: in this expe...
متن کاملMale reproductive health as a sentinel for environmental endocrine disruption
Effects of endocrine disruptors on experimental animals and wildlife are well established. Antiandrogens and estrogens cause reproductive disorders, such as cryptorchidism, hypospadias, testicular dysgenesis and subfertility. This raises a natural question whether these disorders in humans are also caused by endocrine disrupters and whether they should alert us of harmful exposures. While we st...
متن کاملP-4: Grape Seed Extract Alleviate Male Reproductive Toxicity Caused by Busulfan in Rat Model
Background: The alkylating agent busulfan adversely affects spermatogenesis in mammals and Impairment of spermatogenesis has been identified as an inevitable side effect of cancer treatment druges then the aim of this study was to investigate the possible protective effects of Grape seed extract with potent antioxidant activity, on busulfan-treated adult male mice. Materials and Methods: In thi...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2020
ISSN: 1477-7827
DOI: 10.1186/s12958-020-00679-9